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See the full definition for spore in the English Language Learners Dictionary. Rhyming Dictionary: Words that rhyme with spore.

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How to use a word that literally drives some people nuts. The awkward case of 'his or her'. Test your knowledge of words related to the season of longer days and vacations. Test your vocabulary with our question quiz! Examples of spore in a Sentence Recent Examples on the Web: Noun For instance, the office has ensured that each Mars rover carried no more than , bacterial spores on any surface exposed to the Martian environment.

First Known Use of spore Noun , in the meaning defined above Verb , in the meaning defined above. History and Etymology for spore Noun New Latin spora seed, spore, from Greek, act of sowing, seed, from speirein to sow — more at sperm Noun combining form borrowed from New Latin -spora spore entry 1.

Definition

We'll connect you with a solution expert who can help you evaluate and select the right services. Drug manufacturing facilities are required to establish facility and process controls to prevent microbiological contamination 21 CFR Bacterial endospores and fungal spores present significant contamination challenges in drug production areas due to their prevalence in the environment and inherent resistance to chemical inactivation. Spore forms of both organisms develop, in part, due to adverse environmental conditions, producing a dormancy that allows the core genetic material to survive until conditions for growth are present.


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While a bacterial endospore, such as Bacillus cereus, demonstrates greater resistance, fungal spores, such as Aspergillus niger, typically demonstrate more resistance to chemical inactivation than other vegetative microorganisms. Many recent observations and Warning Letters demonstrate deficiencies in addressing spore control.

Pollen and Spores

Control of bacterial and fungal spores requires a holistic approach to managing the environment. This approach should include examination of the contributory factors related to introduction of bacterial and fungal spores to the facility and to effective remediation, including facility design, personnel compliance, and cleaning practices.

Poor facility design is one way to assure contamination control problems. It is also very difficult to overcome after the fact. For example, controlling water through source and drainage reduces microbial contamination risk.

Air full of fungi, study reveals

Areas with floor drains, sinks, water drops, pooling or where water damage has occurred are breeding grounds for microorganisms. Further, uni-directional traffic control, with appropriate isolation measures, shields classified production areas from contamination from other areas. Physical barriers to introduction of contamination should be maximized. Humidity and temperature controls are another means to reduce the risk of microbial proliferation. Finally, surfaces should be selected to maximize microbial control measures e.

Human beings are the most portable and proliferate source of microbial contamination, directly and indirectly. Directly, people shed particulate and accompanying this particulate are microorganisms.